Investigating ALS pathogenesis through multi-disciplinary approaches
Multi-faceted investigation involving chromatin organization, purine metabolism, and DNA damage mechanisms in Amyotrophic Lateral Sclerosis.
Eight years of expertise using zebrafish models to study regeneration and neurodegenerative disorders with cutting edge molecular biology and imaging techniques.
Advanced tools and methodologies for neuroscience research
Live imaging, Confocal microscopy and Brightfield microscopy for in vivo studies.
Hi-C chromatin architecture mapping, ATAC-Seq chromatin accessibility profiling, single-cell RNA sequencing, and custom bioinformatics workflows.
Custom software/tools including the NMJ Analyser for automated image analysis.
Latest contributions to neuroscience research
Investigating the role of PAICS in DNA damage mechanisms and cerebellar neuronal degeneration in C9orf72-related Amyotrophic Lateral Sclerosis.
Read MoreA novel automated and unbiased method for analyzing neuromuscular junction morphology in zebrafish model systems.
Read MoreLet's advance neuroscience research together through innovative approaches.