Jaskaran Singh

PhD Candidate in Neuroscience

I work on: Neuromuscular and Neurodevelopmental Disorders Zebrafish Genetics Bioinformatics and Data Analysis

8+
Years Research Experience
5
Published Articles
PhD
INRS, Quebec
2
Software/Tools Developed

Current Research Focus

Investigating ALS pathogenesis through multi-disciplinary approaches

ALS & Chromatin Organization

Multi-faceted investigation involving chromatin organization, purine metabolism, and DNA damage mechanisms in Amyotrophic Lateral Sclerosis.

Zebrafish Disease Models

Eight years of expertise using zebrafish models to study regeneration and neurodegenerative disorders with cutting edge molecular biology and imaging techniques.

Technical Expertise

Advanced tools and methodologies for neuroscience research

Advanced Imaging

Live imaging, Confocal microscopy and Brightfield microscopy for in vivo studies.

Multi-omics Analysis

Hi-C chromatin architecture mapping, ATAC-Seq chromatin accessibility profiling, single-cell RNA sequencing, and custom bioinformatics workflows.

Tool Development

Custom software/tools including the NMJ Analyser for automated image analysis.

Key Publications

Latest contributions to neuroscience research

2026 Brain

PAICS is a critical mediator of DNA damage and subsequent cerebellar neuronal loss in C9orf72 ALS

Investigating the role of PAICS in DNA damage mechanisms and cerebellar neuronal degeneration in C9orf72-related Amyotrophic Lateral Sclerosis.

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2023 Bioinformatics

NMJ analyser: A novel method to quantify neuromuscular junction morphology in zebrafish

A novel automated and unbiased method for analyzing neuromuscular junction morphology in zebrafish model systems.

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Interested in Collaboration?

Let's advance neuroscience research together through innovative approaches.